/* The research library extends the existing cyan / violet brand. */
.research-hero{padding-block:76px 42px}.research-hero h1{font-size:clamp(48px,6vw,82px);letter-spacing:-4px;margin:24px 0}.research-hero h1 span{background:linear-gradient(100deg,#62f8ee,#adadff,#eb9ce9);background-clip:text;-webkit-background-clip:text;color:transparent}.research-lead{display:grid;grid-template-columns:1.2fr 1fr;gap:100px}.research-lead>p{font-size:17px;max-width:565px;line-height:1.8}.research-lead .curation-note{font-size:12px;align-self:end;max-width:390px;color:#93a8c2}.research-metrics{display:flex;gap:58px;border-block:1px solid var(--line);padding:26px 0;margin-top:35px}.research-metrics>span{font-size:26px;font-weight:600;color:#e3f6fa;line-height:1.3}.research-metrics small{display:block;color:#91a8c1;font-size:10px;letter-spacing:.5px;font-weight:400;margin-top:6px}.research-metrics time{font-size:20px}.research-workspace{padding-bottom:85px}.research-tools{display:grid;grid-template-columns:1fr 230px auto;gap:16px;align-items:end}.research-search{margin:0;min-width:0;height:53px;background:#0d1729;border:1px solid #32435e;border-radius:7px;max-width:none;width:100%}.research-search input{font-size:14px;width:100%;min-width:0}.evidence-select-label{position:relative;font-size:10px;color:#a5b5cb}.evidence-select-label select,.mobile-compound-label select{display:block;margin-top:5px;width:100%;height:53px;background:#0d1729;color:#e7f3ff;border:1px solid #32435e;border-radius:7px;padding:0 35px 0 15px;font:inherit;font-size:13px}.evidence-select-label select:focus-visible,.mobile-compound-label select:focus-visible{outline:2px solid var(--cyan);outline-offset:4px}.research-reset{height:53px;border:0;background:transparent;padding:0 14px;font-size:12px;color:#b5cbe1;text-decoration:underline;text-underline-offset:4px}.evidence-key{display:flex;align-items:center;gap:20px;padding:18px 0 30px;font-size:8px;letter-spacing:.7px;color:#7e9bb9}.evidence-key span:before{content:'•';color:var(--cyan);padding-right:6px}.evidence-key>a{margin-left:auto;letter-spacing:0;font-size:10px;color:#b2c9da}.research-layout{display:grid;grid-template-columns:228px minmax(0,1fr);gap:40px}.compound-sidebar{align-self:start;position:sticky;top:110px;max-height:calc(100vh - 135px);overflow-y:auto;scrollbar-width:thin;scrollbar-color:#314964 transparent;padding-right:8px}.sidebar-heading{display:flex;justify-content:space-between;align-items:center;padding:0 6px 17px;border-bottom:1px solid var(--line);margin-bottom:10px}.sidebar-heading h2{font-size:13px;letter-spacing:0;font-weight:600}.sidebar-heading>span{font-size:10px;color:var(--cyan)}.compound-nav-all,#compound-navigation button{width:100%;display:flex;align-items:center;justify-content:space-between;text-align:left;background:transparent;color:#aebfd4;border:1px solid transparent;border-radius:5px;font-size:12px;line-height:1.4;padding:10px 11px;margin:2px 0;gap:10px}.compound-nav-all{margin-bottom:9px;padding-block:12px}.compound-nav-all[aria-pressed=true],#compound-navigation button[aria-pressed=true]{border-color:#28616c;background:#12313e;color:#6ffff2}.compound-nav-all:hover,#compound-navigation button:hover{background:#122338;color:#e6f6ff}#compound-navigation small{color:#7292aa;font-size:9px;min-width:18px;text-align:center}#compound-navigation button:focus-visible{outline-offset:-2px}.mobile-compound-label{display:none}.research-main{min-width:0}.research-result-bar{display:flex;align-items:center;justify-content:space-between;gap:16px;border-bottom:1px solid var(--line);padding:0 0 16px;margin-bottom:27px}.research-result-bar>p{font-size:12px;color:#bac9d9}.research-result-bar>span{font-size:8px;letter-spacing:1.3px;color:#8297b3}.research-overview-intro{margin-bottom:26px}.research-overview-intro h2{font-size:32px;line-height:1.18;margin-bottom:16px;letter-spacing:-1px}.research-overview-intro h2 span{color:#9daccc}.research-overview-intro p{max-width:610px;font-size:12px;line-height:1.8}.compound-overview-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:17px}.compound-overview-card{padding:23px;text-align:left;display:flex;flex-direction:column;background:linear-gradient(135deg,#112036,#0c1428);border:1px solid #2b3c56;border-radius:9px;min-width:0;transition:border-color .2s,transform .2s}.compound-overview-card:hover{border-color:#488b96;transform:translateY(-2px)}.overview-count{display:flex;align-items:center;justify-content:space-between;color:var(--cyan);font-size:9px;letter-spacing:1px;text-transform:uppercase;margin-bottom:20px}.overview-count>span{font-size:18px;line-height:1}.compound-overview-card h3{font-size:24px;margin-bottom:13px}.compound-overview-card p{font-size:12px;line-height:1.8;margin-bottom:20px}.overview-evidence{font-size:9px;line-height:1.5;color:#d0b5ed;margin-top:auto;padding-top:8px}.overview-reviewed{font-size:8px;letter-spacing:.2px;color:#839ab6;margin-top:12px}.compound-research-section+.compound-research-section{margin-top:56px;padding-top:40px;border-top:1px solid #3a4b64}.compound-section-heading{display:flex;justify-content:space-between;gap:20px;align-items:flex-start}.compound-section-heading h2{font-size:38px;margin:12px 0 8px;overflow-wrap:anywhere}.compound-section-heading .eyebrow{font-size:8px}.compound-aliases{font-size:10px;color:#8fa5c0;line-height:1.7}.review-date{font-size:9px;white-space:nowrap;padding-top:2px;color:#8fa5c0}.review-date time{display:block;color:#bfcfe0;margin-top:3px}.compound-research-summary{font-size:14px;line-height:1.8;margin:20px 0}.evidence-gap{background:#20203a;border-left:2px solid #b995e6;padding:17px 20px;margin:24px 0}.evidence-gap>span{font-size:8px;letter-spacing:1.2px;color:#d5b9ef}.evidence-gap>p{font-size:12px;line-height:1.8;color:#bcc6dc;margin-top:7px}.regulatory-note{padding:16px 20px;background:#0f2c34;border:1px solid #285965;border-radius:7px;margin-bottom:24px}.regulatory-note p{font-size:12px}.regulatory-note a{font-size:11px;color:var(--cyan);display:inline-block;margin-top:12px}.paper-list{display:grid;gap:20px}.paper-card{border:1px solid #2c3d56;border-radius:10px;padding:27px;background:#0d172a}.paper-meta{display:flex;flex-wrap:wrap;align-items:center;gap:10px;color:#8fa8c6;font-size:10px;margin-bottom:17px}.evidence-badge{padding:5px 9px;border-radius:4px;line-height:1.3;font-size:9px;font-weight:600;border:1px solid #2c6971;color:#75e6de;background:#15373e}.evidence-badge.animal{border-color:#70556d;color:#eeb9d6;background:#312235}.evidence-badge.lab{border-color:#4b537e;color:#babcf7;background:#202640}.evidence-badge.review{border-color:#695f42;color:#e4d0a7;background:#302c23}.evidence-badge.registry{border-color:#616b79;color:#c8d6e6;background:#26303c}.paper-card h3{font-size:23px;line-height:1.3;letter-spacing:-.45px;margin-bottom:11px;overflow-wrap:anywhere}.paper-citation{font-size:11px;line-height:1.7;color:#9eb3cd}.paper-doi{font-size:10px;color:#7d96b6;overflow-wrap:anywhere;margin-top:5px}.paper-population{margin-top:19px;display:grid;grid-template-columns:92px minmax(0,1fr);gap:16px;padding:17px 0;border-block:1px solid #243750}.paper-population>span{font-size:8px;letter-spacing:1px;color:#729ab5;padding-top:3px}.paper-population p{font-size:12px;line-height:1.8}.paper-population strong{font-weight:500;color:#d4e5f3}.paper-summary{margin:20px 0 0;display:grid;gap:18px}.paper-summary>div{display:grid;grid-template-columns:92px minmax(0,1fr);gap:16px}.paper-summary dt{font-size:10px;color:#dce9f6;line-height:1.6}.paper-summary dd{margin:0;color:#b0c3d9;font-size:12px;line-height:1.85}.paper-limit dt{color:#d8bcec}.identity-note{font-size:11px;line-height:1.85;color:#b8b9d5;margin-top:22px;background:#1b223a;border-radius:5px;padding:13px 16px}.identity-note strong{font-weight:500;color:#d5caec}.paper-links{display:flex;gap:10px;flex-wrap:wrap;margin-top:25px}.paper-links>a{font-size:10px;color:var(--cyan);border:1px solid #2b5360;background:#102d38;border-radius:4px;padding:8px 12px;line-height:1.5}.paper-links>a:hover{background:#19434d;border-color:#48858a}.source-access{font-size:9px;color:#8096b1;line-height:1.7;margin-top:12px}.research-empty{padding:40px 25px;border:1px dashed #3d5873;border-radius:9px}.research-empty h2{font-size:27px}.research-empty p{font-size:13px;line-height:1.8;margin:17px 0 24px}.research-empty a{color:var(--cyan)}.library-method{display:grid;grid-template-columns:1fr 1.8fr;gap:65px;border-top:1px solid var(--line);padding-block:65px 90px}.library-method h2{margin:21px 0;font-size:35px}.library-method>div>p{font-size:12px;line-height:1.9;margin-bottom:24px}.library-method .text-link{color:var(--cyan)}.method-content details{border-bottom:1px solid var(--line)}.method-content details:first-child{border-top:1px solid var(--line)}.method-content summary{font-size:13px;padding-block:22px}.method-content .details-content p{font-size:12px}.research-footer{display:flex;align-items:center;gap:35px;padding-block:40px}.research-footer p{font-size:10px}.research-footer>a:last-child{margin-left:auto;font-size:11px;color:var(--cyan)}#research-results{scroll-margin-top:110px;outline:none}#research-results:focus-visible{outline:1px solid #356b75;outline-offset:9px}
@media(max-width:1150px){.research-layout{gap:25px;grid-template-columns:196px minmax(0,1fr)}.research-lead{gap:55px}.compound-overview-card{padding:20px}.compound-overview-card h3{font-size:22px}.research-result-bar>span{display:none}.research-hero h1{font-size:65px}.paper-card{padding:23px}}
@media(max-width:900px){.research-hero{padding-top:52px}.research-hero h1{font-size:58px;letter-spacing:-2.5px}.research-lead{gap:32px}.research-lead>p{font-size:15px}.research-lead .curation-note{font-size:11px}.research-tools{grid-template-columns:1fr 195px auto;gap:10px}.research-search input{font-size:12px}.research-layout{grid-template-columns:170px minmax(0,1fr);gap:20px}.compound-overview-grid{grid-template-columns:1fr}.compound-sidebar{top:98px}.compound-nav-all,#compound-navigation button{font-size:10px;padding:9px 8px}.paper-card h3{font-size:21px}.compound-section-heading{display:block}.review-date{display:flex;gap:5px;margin-top:12px}.review-date time{margin:0}.paper-population,.paper-summary>div{grid-template-columns:1fr;gap:6px}.paper-population>span{font-size:8px}.paper-summary dt{font-size:11px}.evidence-key{flex-wrap:wrap;gap:10px 17px}.evidence-key>a{margin-left:0}.library-method{gap:35px;grid-template-columns:1fr 1.5fr}.library-method h2{font-size:29px}.research-footer{flex-wrap:wrap;gap:14px 25px}}
@media(max-width:600px){.research-hero{padding-block:39px 26px}.research-hero h1{font-size:47px;letter-spacing:-2.4px;margin:20px 0}.research-hero .eyebrow{font-size:7px;letter-spacing:1.6px}.research-lead{grid-template-columns:1fr;gap:17px}.research-lead>p{font-size:14px;line-height:1.8}.research-lead .curation-note{font-size:11px;max-width:100%}.research-metrics{gap:0;justify-content:space-between;padding-block:20px;margin-top:25px}.research-metrics>span{font-size:23px}.research-metrics small{font-size:8px;letter-spacing:0;max-width:100px}.research-metrics time{font-size:14px}.research-tools{grid-template-columns:1fr 53px;gap:12px;align-items:center}.research-search{grid-column:1/-1;height:50px}.research-search input{font-size:13px}.evidence-select-label{font-size:9px}.evidence-select-label select{height:45px;margin-top:4px;font-size:12px}.research-reset{height:44px;margin-top:19px;padding:0;font-size:11px}.evidence-key{padding:16px 0 21px;font-size:6px;gap:9px 10px;letter-spacing:.35px}.evidence-key>a{font-size:9px;flex-basis:100%}.research-layout{grid-template-columns:1fr;gap:24px}.compound-sidebar{position:static;max-height:none;overflow:visible;padding:0}.sidebar-heading,#compound-navigation,.compound-nav-all{display:none}.mobile-compound-label{display:block;color:#abc2d9;font-size:10px}.mobile-compound-label select{height:46px;font-size:13px;margin-top:7px}.research-result-bar{padding-bottom:14px;margin-bottom:24px}.research-result-bar>p{font-size:11px}.research-overview-intro h2{font-size:29px;line-height:1.2}.research-overview-intro p{font-size:12px}.compound-overview-grid{gap:14px}.compound-overview-card{padding:23px}.compound-overview-card h3{font-size:25px}.compound-overview-card p{font-size:12px}.overview-count{font-size:9px;margin-bottom:16px}.overview-evidence{font-size:9px}.overview-reviewed{font-size:8px}.compound-section-heading h2{font-size:33px}.compound-research-summary{font-size:13px}.evidence-gap{padding:17px;margin:21px 0}.evidence-gap p{font-size:11px}.paper-card{padding:21px 18px;border-radius:8px}.paper-meta{gap:8px;font-size:9px;line-height:1.5}.paper-card h3{font-size:21px;line-height:1.3}.paper-citation{font-size:10px}.paper-doi{font-size:9px}.paper-population p,.paper-summary dd{font-size:12px}.paper-summary{gap:17px}.paper-summary dt{font-size:11px}.paper-links{gap:8px;margin-top:21px}.paper-links a{font-size:10px;padding:9px}.source-access{font-size:9px}.identity-note{font-size:10px;padding:13px}.library-method{grid-template-columns:1fr;gap:27px;padding-block:44px 55px}.library-method h2{font-size:32px}.method-content summary{font-size:12px}.method-content .details-content p{font-size:11px}.research-workspace{padding-bottom:50px}.research-footer{display:grid;grid-template-columns:1fr auto;gap:13px;padding-block:30px}.research-footer .footer-brand{grid-column:1/-1;font-size:21px}.research-footer p{font-size:9px}.research-footer>a:last-child{font-size:9px}#research-results{scroll-margin-top:95px}}